The world’s most beloved speedrunning marathon kicks off today (Jan. 7) at 11:30am ET on Twitch.

Games Done Quick (GDQ) is a speedrunning event that only happens twice per year. Thousands of viewers watch their favorite speedrunners destroy some of their beloved games and, in turn, donate millions of dollars to charity. The runners come from all corners of the globe, and it’s easily the world’s biggest speedrunning event.

This year, AGDQ will be benefiting the Prevent Cancer Foundation, an organization that helps to detect and prevent cancer before it spreads.

JHobz is kicking off the event this year with the popular speedgame Crash Bandicoot N.Sane Trilogy. The event will then continue for the next seven days without any stops as speedrunners attempt to complete 155 games as fast as possible.

Fans can also support AGDQ this year by buying merchandise from either Fangamer or TheYetee. A percentage of all sales will go towards the Prevent Cancer Foundation.

Now that AGDQ is here, it’s time to rally the speedrunning community to help a great cause.

AGDQ 2018 kicks off today